Diabetes

Basaglar vs Lantus – Differences Between Them?

Diabetes patients also need insulin to regulate their blood sugar levels. However, considering there are several insulins that are similar in nature, choosing which insulin can be difficult. So, we’ll talk about Lantus vs. Basaglar in this article to help you better understand the differences and similarities.

Before we dig deep into all the details; Insulin glargine is used for the treatment of patients with type 1 and type 2 diabetes, and Lantus and Basaglar are types of this Insulin glargine. They are very similar to long-acting insulins but are not interchangeable.

 

What is Insulin Glargine?

Insulin glargine is a long-acting, man-made insulin. Type 1 diabetes patients can use insulin glargine together with quick-acting insulin. Type 2 diabetes patients may use insulin glargine on their own or together with any other insulin to treat their condition.

Insulin glargine is injected under the skin, every day at the same time. It should not be injected if you are showing symptoms of low blood sugar. This drug will either come in insulin pens or vials.

You should not combine insulin glargine with another insulin or substitute this form of insulin with some other type of insulin without talking to your doctor. Also, this form of insulin should never be used in the insulin pump.

Basaglar Insulin

Basaglar is a prescription drug used to boost blood sugar levels in adults and children (6 years and older) with type 1 diabetes and adults with type 2 diabetes. Basaglar contains insulin glargine and is a long-acting insulin type. Basaglar comes in a liquid form and is given as an injection under your skin.

The medication comes in two forms; the Basaglar KwikPen, which holds 3 milliliters (ml of solution), and the Basaglar Tempo Pen, which is a pen that can be connected to a mobile app to record your insulin dose. Tempo Pens also holds 3 ml of solution. Each ml of Basaglar solution consists of 100 units of insulin glargine.

 

Lantus Insulin

Lantus is also a prescription drug used to improve blood sugar levels in adults and children (6 years and older) with type 1 diabetes and adults with type 2 diabetes. Lantus contains insulin glargine and is a long-acting form of insulin. Lantus is also given as an injection under your skin.  The medication comes as a solution inside a 10 milliliter (ml) vial containing 100 units of insulin glargine per ml. Needles are used with the vial which is not part of the vial.

Lantus comes as a pre-filled SoloStar pen, too.  Each pen consists of 3 ml of drug solution with 100 units of insulin per ml of solution.

 

To get more info on Basaglar (Click Here) and for Lantus (Click Here).

 

Similarities and Differences Between Lantus and Basaglar

Similarities and differences

Basaglar and Lantus are remarkably similar because they contain insulin glargine; they also have the same amino acid chain sequence. They are not only adopted in the same way but are also equal in terms of protection and efficacy.

Basaglar is referred to as a follow-up drug to Lantus. This indicates that it is very similar to Lantus, which is a biological drug. Biologic medications are made from living cells in a laboratory. Follow-up medications are somewhat similar to the original biologic drug. Even though Basaglar is a follow-up to Lantus, it’s not a generic medication. Generic medications contain correct copies of the active ingredient of the brand name drug.

The differences between these two medications are relatively small. First of all, various companies develop these medications and distribute them in different ways. Although they are relatively similar in price, Basaglar is currently a slightly cheaper choice in the United States. These price adjustments can, however, be on the basis of insurance. Lastly, Basaglar is only available as a pre-filled 3 ml pen (100 units/mL (U-100) injection) while Lantus is available as both a 10 ml multi-dose vial and a 3 ml single-patient pen (both 100 units/mL (U-100) injection).

There is no clear response when it comes to deciding which one is better between Lantus and Basaglar. Since Basaglar is a biosimilar, it provides individuals with the same effect as Lantus. More precisely, the best choice for you can depend on which one your insurance cover more.

The Food and Drug Administration (FDA) finds that follow-on insulin is as safe and successful as the initial drug. This means that Basaglar increases blood sugar levels just as Lantus does. It also means that Basaglar and Lantus have similar side effects.

 

Common Side Effects of Basaglar and Lantus

side effects

Low blood sugar (hypoglycemia) is the most common side effect of both Lantus and Basaglar Insulin. Hypoglycemia is severe and can be life-threatening. Symptoms of hypoglycemia include:

  • Mood changes
  • Confusion
  • Sweating
  • Dizziness or Drowsiness
  • Increased heartbeat
  • Blurry vision
  • Confusion
  • Headaches
  • Anxiety
  • Hunger

Other potential side effects of Basaglar Insulin Glargine include:

  • Edema (swelling in the legs, ankles, or feet)
  • Reactions at the injection site
  • Skin rash
  • Cold infections
  • Weight gain
  • Allergic reactions

Other potential side effects of Lantus Insulin Glargine include:

  • Swelling up
  • Increase in weight
  • Low levels of potassium in the body
  • Reactions at the injection site (itchiness, pain, or redness around the area)
  • Changes in fat tissue at the injection site
  • Allergic reactions
  • Upper respiratory infections
  • Edema (swelling in the legs, feet, or ankles)

 

Basaglar and Lantus Dosage

Below is a well-detailed tabular form of the Basaglar and Lantus dosage for children and any adult with type 1 or type 2 diabetes.

Insulin Type Type 1 Diabetes Dosage Type 2 Diabetes Dosage Children Dosage
Basaglar Insulin Glargine  

Starting dose is one-third of your total daily insulin dose (the rest of the required daily dose will be given as insulin during meals).

 

Total insulin dose per day is based on body weight in Kilograms (kg).

The dose ranges from 0.4 units/kg to 1 unit/kg daily

 

Starting dose is 0.2 units per kg of your body weight.

 

The maximum starting dose is 10 units per day.

Dosage for children with type 1 diabetes is similar with the adult dosage.

 

One-third of the daily dosage is taken at first and the rest is given as mealtime insulin.

Total daily dose is based on the weight of the child in kilograms (kg) and can range from 0.4 units/kg to 1.0 units/kg

 

Lantus Insulin Glargine Starting dose is one-third of your total daily dosage.

 

Daily dose ranges from 0.4 to 1.0 units/kg a day.

 

Dosage is administered just once a day.

 

Starting dose is 0.2 units/kg and the maximum dose a day is 10 units/kg.

 

Dosage is administered just once a day.

 

Starting dose is similar to the dose for adults with type 1 diabetes.

 

 

Daily dose is based on the child’s weight and ranges from 0.4 units/kg to 1.0 units/kg.

 

Note: if a dose is missed, make sure you take it as soon as you remember. Although if it’s time for the next dose when you remember just skip the missed dose. But always remember to take your doses at the same time every day and make sure you don’t take more than one dose within 24 hours unless recommended by your doctor.

So do well to set a reminder on your phone or alarm clock or get a medication timer, which has proven to be very useful.

 

Basaglar and Lantus Interactions

Basaglar and Lantus Interactions

Basaglar and Lantus can interact with several other drugs. It can also interact with some supplements as well as certain foods. Different interactions can have various effects. For example, some experiences can interfere with how well a drug works. Other interactions can increase or make side effects more severe.

Below is a list of drugs that may interact with Basaglar and Lantus (these lists do not include all drugs that may interact with them). Speak to your doctor and pharmacist before taking Basaglar. Inform them about all the prescriptions, and other medications you’re taking. Tell them about any vitamins, herbs, and supplements you are currently using. Sharing this knowledge may help to prevent future encounters.

If you have any concerns about medication interactions that can concern you, ask your doctor or pharmacist.

Basaglar and Lantus with a thiazolidinedione

A diabetes drug that can cause heart failure or worsen your condition if you have a history of heart failure. Examples of thiazolidinedione include rosiglitazone (Avandia), and pioglitazone (Actos).

Basaglar and Lantus with certain diabetes drugs

They can increase your risk of having hypoglycemia (low blood sugar level). Your doctor has to be informed before taking Basaglar with these drugs so your dosage for one or both may be changed. Examples of these certain diabetes drugs are metformin (Glumetza, Glucophage), pramlintide (Symlin), mealtime insulins (including glusine), and insulin aspart (Fiasp, Novolog).

Basaglar and Lantus with a corticosteroid

This can raise the chances of having serious complications as this corticosteroid decreases the effectiveness of Basaglar which can lead to high blood sugar levels. Examples of corticosteroids are prednisone (Rayos), prednisolone (Orapred, Prelone), methylprednisolone (Medrol), and hydrocortisone (Cortef).

Basaglar and Lantus with some blood pressure drugs

They can mask symptoms caused by hypoglycemia (low blood sugar level) thus preventing you from treating it because you are unaware. Examples of these drugs are atenolol (Tenormin), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), propranolol (Catapres, Kapvay), and reserpine.

 

Cost Price Difference

Cost and price

Basaglar is cheaper than Lantus, but it’s still really costly for individuals. Prices for these medications vary as with all medications.

The actual price depends on location and insurance plan.

To get a quick overview on cost price for Basaglar (Click Here) and for Lantus (Click Here).

 

Overdose Symptoms

Basaglar Overdose Symptopms

Overdose of Basaglar or Lantus can lead to:

  • Hypokalemia (low potassium levels)
  • Weakness
  • Constipations
  • Extra or Skipped heartbeats
  • Hypoglycemia (low sugar levels)
  • Coma
  • Seizures

 

Basaglar and Lantus Precautions

Consult your doctor about your health history before taking Basaglar or Lantus. Basaglar or Lantus might not be right for you if you have some medical conditions that include:

  • Allergic reaction to Basaglar or Lantus
  • Hypokalemia (low potassium levels)
  • Current episode of hypoglycemia

 

Conclusion

Healthmedsplus has made every attempt to ensure that all information provided is factually accurate, thorough, and up-to-date. Nevertheless, this article should not be used as a replacement for the experience and training of a licensed health practitioner. Before taking any drug, you should first contact your doctor or other health care provider. The medication information contained herein is changeable and is not intended to cover all potential uses, instructions, precautions, signs, drug interactions, allergic reactions, or adverse reactions. The lack of warnings or other information on a given medication does not mean that a combination of drugs or drugs is safe, successful, or appropriate for all patients or all specific uses.

If you need more info on Insulin (visit this link) and if you need info on the most recommended click here or here.

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